shot placement is everything, my late uncle, many years back, finally confessed to never being without venison...we'll leave it at that, he said he took more deer with a 22 hornet, I decided to stay on the right side of the laws...I had a ruger #1 in 22 hornet loved it, but a very limited round, one gun...lever 30-30 win period, will not only kill any animal in the west but will drop them in their tracks, cheap ammo, accurate, and Deadly, even for home protection, think about when the west was wild...what did they own....they owned a rifle in the same caliber as their handgun...32 cal lever and 32 cal 6 shooter, they could protect the family and bring home the bacon. That being said I love 22-250, .270, 30-06, 243, 7mm, 223, etc, etc. You can't have too many:archer green:a .22 will kill anything in CA
.300 winmag...you can't kill something too dead.
Remington 870 WM with a 28" ventilated rib and a slug barrel. From doves to elk it will do it all. Load it with buck shot and you have your home defense covered as well.